You might want to know how nootropics work to achieve their stimulating effects. It is worth noting that the nervous system is quite broad and complex, compounded by the fact that there exist various types of nootropics that work differently. This makes such a question quite complex too. But in a nutshell, nootropics work by improving the efficiency of neurotransmitters in the brain and increasing the functionality of aspects of the nervous system concerned with cognitive function. In this case, the system is a neurotransmitter together with its associated receptors. The effects nootropics have also vary depending on the type of the neurotransmitter/receptor system. These effects are elaborated below based on the specific neurotransmitter/receptor system;
This neurotransmitter/receptor system is reliant on Acetylcholine that affects the cognitive function of the brain. It impacts learning, decision-making, concentration and memory. Nootropics will increase the levels of Acetylcholine neurotransmitters which enable effective communication between the neurotransmitters and receptors and subsequently improving the brain function. Nootropics that affects this system are may cause headache which is one of the side effects.
Dopaminergic and serotonergic system
The dopaminergic and serotonergic neurotransmitters are part of the central nervous system responsible for motivation, mood, reward and some aspects of memory and focus. Nootropic drugs will act on the nervous system by affecting certain dopamine and serotonin neurotransmitters and receptors. Such may improve the mood of users and other brain functions. On the flipside, nootropics that affect the dopaminergic and serotonergic system are quite addictive and it is advisable not to use them on a regular basis.
Nootropics And Side Effects
This is also another ambiguous question yet again. Nootropics is such a broad subject and the side effects are specific to the type of nootropic being used. Although most people who have used nootropics usually experience headaches, this can be attributed to the fact that the brain is working harder, faster and more efficiently than usual. Some acetylcholine receptors of the brain may also fatigue due to the intensity of brain action. However, this side effect can be countered by consuming choline; Alpha GPC is recommended to increase its supply and meet the brains demand for chemicals in order to relieve the headaches. Excessive dosses of nootropics may be hard for the digestive system especially in the intestines. This can cause stomach discomforts, diarrhea, nausea and pains in the stomach. The remedy for this side effect is to reduce the dosage or use a more concentrated nootropic such as noopept that requires less processing in the digestive tract.
Use of nootropics before going to bed or in the evenings can cause fatigue or even insomnia. The nootropics will increase the energy levels and keep the user alert. This will hamper the quality of sleep and cause insomnia or fatigue as the user does not get enough rest. It is recommended to avoid the use of nootropics before going to bed or late in the evening (with exception to Phenibut which helps against insomnia). Another long term side effect that you can be wary of is that nootropics may be addictive in the long run. Being stimulants, prolonged use of nootropics can make the brain to become dependent on the drugs in order to function effectively. Therefore prolonged use of the nootropics should be avoided.
Phenibut is the only nootropic that should be taken before bedtime as it helps you sleep