We put some of the “best” brain supplements on the market to the test, far from all of them works, but some do and we ranked the top 5 nootropics on this website! Continue reading and simply click one of the nootropics you would like to know more about!

Recent studies have shown that nootropics are widely used among young CEO’s to improve focus and cognitive function.
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Memory And Concentration Boost

To boost your memory and ability to concentrate and focus we recommend some of of the following nootropics:





Boost In Productivity And Thought Process

For a more soothing, yet boosting effect on your productivity, motivation and for a more calm though process, try:


Nootropics For Anxiety And Stress

To ease your anxiety and stress we recommend:



What Are Nootropics?

Most food and drug supplements are geared towards improvement of the body functions and immune system. They aim for a healthy body and prevention of diseases. It is quite rare to find supplements that are focused on improving the brain function and central nervous system. This is obviously due to the fact that most supplements that affect the brain function are considered to be drugs such as alcohol and marijuana. But you might have come across nootropics, a drug supplement that is renowned for its ability to influence the human brain. Well, I got something to tell about nootropics too, though it is quite a complex subject as it focuses on the central nervous system, an obviously complex part of human biology for most of us.

Nootropics are drugs that improve the various aspects of mental function when taken, such as memory and attention. The drugs are a fusion of supplements and neurochemicals usually used for boosting memory, attention and to improve the brainpower. They commonly referred to as neuro enhancers, intelligence enhancers and or smart drugs.

Stimulates The Nervous System

Nootropics are widely used for medicinal purposes in the treatment of cognitive difficulties and motor dysfunction that may be caused by disorders such as Parkinson’s disease, Huntington’s disease and ageing. Nootropic drugs are also widely used as stimulants for the nervous system. This can be attributed to its availability and intense marketing by manufacturers and distributors who mostly label the drug as food supplements. However, there is growing concern for further research on nootropics to develop reliable information about the drug due to its growing demand and consumption.

Nootropics Common Among Students

Researchers have also found out that the nootropics are commonly used by students to improve their memory and concentration. It is prevalently used by students in in competitive academic institutions such as high schools, colleges and universities.

Do Nootropics Work?

You might want to know how nootropics work to achieve their stimulating effects. It is worth noting that the nervous system is quite broad and complex, compounded by the fact that there exist various types of nootropics that work differently. This makes such a question quite complex too. But in a nutshell, nootropics work by improving the efficiency of neurotransmitters in the brain and increasing the functionality of aspects of the nervous system concerned with cognitive function. In this case, the system is a neurotransmitter together with its associated receptors. The effects nootropics have also vary depending on the type of the neurotransmitter/receptor system. These effects are elaborated below based on the specific neurotransmitter/receptor system;

Cholinergic system

This neurotransmitter/receptor system is reliant on Acetylcholine that affects the cognitive function of the brain. It impacts learning, decision-making, concentration and memory. Nootropics will increase the levels of Acetylcholine neurotransmitters which enable effective communication between the neurotransmitters and receptors and subsequently improving the brain function. Nootropics that affects this system are may cause headache which is one of the side effects.

Dopaminergic and serotonergic system

The dopaminergic and serotonergic neurotransmitters are part of the central nervous system responsible for motivation, mood, reward and some aspects of memory and focus. Nootropic drugs will act on the nervous system by affecting certain dopamine and serotonin neurotransmitters and receptors. Such may improve the mood of users and other brain functions. On the flipside, nootropics that affect the dopaminergic and serotonergic system are quite addictive and it is advisable not to use them on a regular basis.

Nootropics And Side Effects

nootropics side effectsThis is also another ambiguous question yet again. Nootropics is such a broad subject and the side effects are specific to the type of nootropic being used. Although most people who have used nootropics usually experience headaches, this can be attributed to the fact that the brain is working harder, faster and more efficiently than usual. Some acetylcholine receptors of the brain may also fatigue due to the intensity of brain action. However, this side effect can be countered by consuming choline; Alpha GPC is recommended to increase its supply and meet the brains demand for chemicals in order to relieve the headaches. Excessive dosses of nootropics may be hard for the digestive system especially in the intestines. This can cause stomach discomforts, diarrhea, nausea and pains in the stomach. The remedy for this side effect is to reduce the dosage or use a more concentrated nootropic such as noopept that requires less processing in the digestive tract.

Avoid Before Bedtime

Use of nootropics before going to bed or in the evenings can cause fatigue or even insomnia. The nootropics will increase the energy levels and keep the user alert. This will hamper the quality of sleep and cause insomnia or fatigue as the user does not get enough rest. It is recommended to avoid the use of nootropics before going to bed or late in the evening (with exception to Phenibut which helps against insomnia). Another long term side effect that you can be wary of is that nootropics may be addictive in the long run. Being stimulants, prolonged use of nootropics can make the brain to become dependent on the drugs in order to function effectively. Therefore prolonged use of the nootropics should be avoided.

Phenibut is the only nootropic that should be taken before bedtime as it helps you sleep

Most Popular Nootropics –

These are the Best Nootropics we tried!


The noopept as a nootropic supplement but is categorized in the Racetam family of drugs since it has similar mechanisms of action with the Racetam family. It is considered to be the strongest and most effective nootropic supplement in the market. It is mostly promoted and distributed in Russia and neighboring countries as a smart drug. In the US, it is sold as a dietary supplement while in other countries; it is mostly sold as medication. It has a myriad of benefits; improving memory, focus, concentration and learning of the users. It has neuro-protectant properties that enable the supplement to protect brain neurons from damage and support the overall health of the brain.


GABA is the so called “chief inhibitory neurotransmitter” in the CNS (Central Nervous System) and it is basically calming the nervous system down by binding to specific receptors in the brain. What this does is simply calming down the neurons. However, there are questions as to the effectiveness of this supplement, as it is not able to pass the so called blood-brain-barrier, which means it does not actually enter the brain. Even so, there are several studies suggesting it may have beneficial effects for those seeking a relief of symptoms of for instance light anxiety or insomnia.

GABA Review


This is a Racetam supplement prototype with two nitrogen compounds in its structure and is soluble in water. One thing that makes Piracetam different from other nootropics is that it is non-stimulatory and non-sedative whereas nootropics are stimulants. It works by enhancing the permeability of cell membranes in the brain which improves the diffusion of oxygen molecules into the brain cell and elimination of toxins and waste. It is medically used as a neuro-protective agent before or after stroke. Its use also improves memory especially pertaining to sensory perception of sight, smell and touch. It also improves mental energy and can be a remedy for anxiety and sleep disorders.


Pramiracetam is derived from the parent Racetam by synthesizing Paracetam. It is a newer nootropic and acst by influencing Glutamate at the Acetylcholine receptor stes; this improves the efficiency and reuptake of these brain sites which is dependent on the adrenal glands. It also influences the uptake of choline into the hippocampus; a section of the brain concerned with storage of new information. Pramiracetam improves blood flow to the brain which increases oxygen uptake in the brain which thus catalyzes the metabolism of glucose. The resulting increased mental energy causes longer attention spans, better focus and faster thinking of the brain. As is common with all nootropics, Pramiracetam increases memory and learning capacity.


The Phenibut is a neuro-psychotropic drug with cognitive enhancing effects of nootropics that is used for the treatment of various illnesses such as anxiety and insomnia. It is derivative of the naturally occurring inhibitory neurotransmitter gamma-amino butyric acid (GABA) and has anxiolytic and nootropic cognitive effects on the brain. It has a similar mechanism of action on the brain as alcohol it stimulates which relaxes the muscles, lessens anxiety and provides stimulatory effects. Phenibut has therapeutic effects that enhances cognitive functions of the brain such as attention, learning and memory by improving inter hemispheric transmission; communication between the left and right hemispheres of the brain. It can also be utilized to deal with anxiety and promote a restful sleep.


Adrafinil is classified as a eugeroic, which is a kind of stimulant. It was originally intended for narcolepsy patients to improve daytime wakefulness and alertness and to minimize the effects of fatigue. As a stimulant, it can positively affect mood, increase energy levels, speed up recall, and increase concentration and focus. As adrafinil is metabolized in the body into modafinil, there are certain precautions that must be taken into consideration.

Pyrroloquinoline Quinone (PQQ)

Discovered in 1979 inside a bacteria, pyrroloquinoline quinone (PQQ) is similar to vitamin B12. This compound cannot be produced by the body; however, there are many sources of PQQ in different fruits and vegetables including parsley, kiwi, papaya, tofu, etc. Because it aids in the production of new mitochondria, which is responsible for all activities at the cellular level, PQQ is known to improve overall health and well being. In addition, it is also a very potent antioxidant. Its benefits include alertness, increased cognitive performance, enhanced mental and heart health, decreased inflammation, improved quality of sleep, and more.


Sulbutiamine was initially developed in Japan to address vitamin B1 (thiamine) deficiency. Unlike thiamine, sulbutiamine is more easily absorbed in the body as it goes through the intestine and circulates to the bloodstream. It can also cross the blood-brain barrier faster, hence its potency in various cognitive functions can be really noted. Aside from boosting energy and improving the mood, sulbutiamine has also shown promise in the treatment of the symptoms of various conditions like CFD, depression, and social anxiety.


Phosphatidylserine (PS) was first identified in 1942, but the first PS supplements were not developed until the 1990s. Phosphatidylserine is an aminophospholipid that is naturally found in the body, with almost half of the entire PS concentrated in the brain. As a phospholipid with both fatty and amino acids, phosphatidylserine is an essential component in almost all cellular functions. It is seen as one of the most vital building blocks of brain cells. For this reason, phosphatidylserine has a host of benefits that range from improved cognitive function, reduced stress, relieve symptoms of ADHD, Parkinson’s disease, Alzheimer’s disease, anxiety, depression and more.

In a summary, the nootropics is one the top natural supplements touted for having cognitive effects on its users. A variety of research has also been done to determine their medical benefits, most of which have been positive to derive their various benefits especially on the brain. Nootropics also have very few side effects especially when taken in the recommended dosages. Being a stimulant, a user who uses nootropics together with other stimulants such as alcohol, marijuana and coffee may develop some side effects such as stomach discomfort, fatigue, headaches and nausea. It is therefore advisable to avoid using other stimulating drugs together with nootropics. It is also recommended not to use nootropics during pregnancy and lactation.