Adrafinil is a precursor to modafinil, which means that when it is metabolized by the liver, it becomes modafinil. So you might be wondering why take adrafinil when it works much the same way as modafinil? Although closely similar, these eugeroic compounds have its differences that might suit your situation and requirement better than the other.
How Does Adrafinil Work?
As a eugeroic compound, adrafinil is a stimulant. Clinically, it is used to treat sleep disorders and narcolepsy. Today, adrafinil is primarily used to promote wakefulness and alertness. In addition, adrafinil provides cognitive enhancement benefits like increased concentration and focus with a general sense of well-being.
There is no clear understanding to adrafinil’s accurate mechanism of action, but it has been theorized that once it is metabolized into modafinil, it works on adrenergic neurotransmitters, mainly boosting hypocretin levels. When this happens, norepinephrine and dopamine production are also increased. These neurotransmitters play a role in adrafinil’s wakefulness effect.
Further, adrafinil’s ability to inhibit dopamine breakdown is the mechanism responsible for its improved mood and sense of well-being effect. While controlling glutamate breakdown seems to be responsible for its cognitive benefits like increased concentration and focus.
Advantages of Supplementing with Adrafinil
Aside from the cognitive benefits of adrafinil, there are several more advantages to supplementing with this nootropic:
Adrafinil can be bought over the counter without the need for a prescription;
Adrafinil has a long half-life and add to this the modafinil that’s converted in the liver, then the half-life becomes longer, which converts to a longer effect as well;
Adrafinil is a dietary supplement, so it can be easily obtained;
Adrafinil is affordable as compared to modafinil;
Adrafinil is non-habit forming.
Adrafinil is less potent than modrafinil, it being a prodrug. But this does not diminish the fact that it just as effectively provides powerful cognitive and stimulant benefits.
Who Benefits Most from Adrafinil?
Night-shift workers who need to work round the clock during the graveyard shift;
Students who need to study for major exams;
Individuals who have sleeping problems as it boosts wakefulness during the day, but does not interrupt sleeping patterns.
On the Issue of Liver Toxicity
Perhaps the greatest downside you may read about Adrafinil is that it can damage the liver. Liver enzymes are necessary to convert Adrafinil to Modafinil, and this could put a strain on the liver. However, there is no solid proof that this is the case.
But Adrafinil is without side effects as well. Like Modafinil, it can cause an upset stomach, dizziness, nausea, headache, and dry mouth. These side effects are on a case to case basis though. While some may experience these symptoms, there are also users who have not experienced any kind of side effect as long as they supplement within the recommended dosage.
Tips When Buying Adrafinil
Since adrafinil is an unregulated compound, it is legal to buy the supplement. Since it is classified as a supplement and not approved by the FDA, it is not available over the counter. This is the reason why finding the right supplier when you buy Adrafinil is tantamount to maximizing its benefits. Look for an online supplier that has been time-tested to deliver high-grade nootropics, if possible one where their nootropics are validated by third-party laboratories. There are hundreds of online shops where you can buy adrafinil, and in cases like these, reviews and user feedback will point you in the right direction to get quality adrafinil.
Like other nootropics, Adrafinil must not be used for an extended period of time. Cycling is still the best way to supplement. When in doubt, always seek medical advice from your physician. Individuals with existing health conditions especially that of the liver and heart should also consult their physician. Always practice safety first.